NCT06960083

Transcranial Magnetic Stimulation in Misophonia

A Transcranial Magnetic Stimulation Approach to Treat Misophonia

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Icahn School of Medicine at Mount Sinai · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the project is to assess the efficacy of parietal transcranial magnetic stimulation in misophonia. N=60 participants will undergo two transcranial magnetic stimulation sessions: one inhibitory and another excitatory. During both sessions, the parietal region will be stimulated. Participants will perform computerized tasks immediately before and after the stimulation, while EEG, heart rate, and skin temperature will be recorded. These recordings will be used to assess if TMS can be used to improve tolerance to misophonia triggers.

Conditions

• Misophonia

Interventions

Type	Name	Description
OTHER	Transcranial Magnetic Stimulation (TMS)	Transcranial Magnetic Stimulation (TMS) is an FDA-approved non-invasive brain stimulation technology. It is currently used for treating depression. Applications to other disorders such as OCD and anxiety using TMS are currently under investigation. TMS will be administered for 25 minutes.

Timeline

• Start date: 2025-09-02
• Primary completion: 2026-06-30
• Completion: 2026-06-30
• First posted: 2025-05-07
• Last updated: 2025-09-09

Locations

1 site across 1 country: United States