NCT06958965

Resistance Exercise Training on Vascular and Physical Function in Postmenopausal Women

Effects of Resistance Exercise Training on Vascular Function and Physical Performance in Postmenopausal Women

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: National Yang Ming Chiao Tung University · Academic / Other
• Sex: Female
• Age: 55 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Postmenopausal women often face risks of vascular dysfunction and muscle deterioration due to estrogen deficiency. These changes significantly increase the risk of cardiovascular disease and mortality. Previous studies have shown a significant positive correlation between vascular endothelial function and muscle strength. Moreover, muscle strength is a stronger predictor of mortality than muscle mass and is closely associated with the maintenance of functional independence in daily life. However, studies investigating the effects of whole-body progressive resistance training on vascular function and physical performance in postmenopausal women remain limited. This study aims to examine changes in vascular function and muscle strength in postmenopausal women following a whole-body progressive resistance training program.

Conditions

• Postmenopausal Women

Interventions

Type	Name	Description
OTHER	Resistance exercise training	The total duration of the training was 12 weeks, with a frequency of two sessions per week. Each session lasted approximately 90 to 120 minutes. The exercise intensity was set at 40-70% of the participants' one-repetition maximum (1RM), or adjusted based on the Modified Borg Rating of Perceived Exertion (RPE), targeting a moderate intensity level (approximately a score of 3).

Timeline

• Start date: 2025-06-09
• Primary completion: 2025-11-03
• Completion: 2025-11-03
• First posted: 2025-05-06
• Last updated: 2026-03-13

Locations

1 site across 1 country: Taiwan