NCT06955390

Clinical Trial of HRS-4642 Plus SHR-A2102 in Patients With Advanced Solid Tumors

An Exploratory Clinical Study of HRS-4642 in Combination With SHR-A2102 for the Treatment of Advanced Solid Tumors

• Status: Not Yet Recruiting
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 32 (estimated)
• Sponsor: Henan Cancer Hospital · Other Government
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to observe and evaluate the efficacy and safety of HRS-4642 combined with SHR-A2102 in the treatment of advanced solid tumors

Detailed description

This study is a prospective, single-arm, exploratory clinical trial. It plans to enroll patients with advanced solid tumors , treating them with HRS-4642 in combination with SHR-A2102. The entire study is divided into two stages: a safety run-in period and an efficacy exploration period.

Conditions

• Solid Tumors

Interventions

Type	Name	Description
DRUG	SHR-A2102+HRS-4642	A fixed dose was used for SHR-A2102,HRS-4642 can be dose adjusted.

Timeline

• Start date: 2025-05-01
• Primary completion: 2025-12-01
• Completion: 2026-12-01
• First posted: 2025-05-02
• Last updated: 2025-05-02

Locations

1 site across 1 country: China