NCT06955143

A Study on the Peripheral Blood in Patients With Acute Coronary Syndrome

A Study on Integrated Multi-Omics and Multi-Factor Analysis of Peripheral Blood in Patients With Acute Coronary Syndrome

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 310 (estimated)
• Sponsor: Second Affiliated Hospital of Wenzhou Medical University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

The goal of this study is to conduct analyses the changes of cell growth factors, inflammatory factors, metabolites, plasma proteome, etc. in the blood of patients with ACS (acute coronary syndrome), as well as their correlations with the disease prognosis, based on multi-omics or other related research methods. The main questions it aims to answer are: The growth factors that have significant changes in the peripheral blood of the ACS population, especially fibroblast growth factors? Inflammatory factors and chemokines related to the onset of ACS? The metabolites and proteins that are significantly altered in the peripheral blood after the onset of ACS? Researchers will compare ACS population to CCS (Chronic Coronary Syndrome) population, and control group (patients without coronary artery stenosis, valvular heart disease, structural heart disease, or any other kind of cardiomyopathy).The peripheral venous blood from the participants will be collected within 24 hours after their admission to the hospital.

Conditions

• Acute Coronary Syndrome
• Chronic Coronary Syndrome

Timeline

• Start date: 2025-03-11
• Primary completion: 2025-08-01
• Completion: 2025-12-01
• First posted: 2025-05-02
• Last updated: 2025-07-25

Locations

1 site across 1 country: China