NCT06954766

Initial Pilot Study to Evaluate the Safety and Temporary Symptom Improvement Efficacy of CKD-981

A Randomized, Double-blind, Sham-controlled, Initial Pilot Study to Evaluate the Safety and Temporary Symptom Improvement Efficacy of CKD-981 in Patients With Degenerative Knee Osteoarthritis

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Chong Kun Dang Pharmaceutical · Industry
• Sex: All
• Age: 40 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to prove that the temporary symptom improvement effect on knee osteoarthritis using CKD-981

Detailed description

The aim of this pilot study is to evaluate the efficacy and safety of CKD-981 in patients with mild to moderate degenerative knee osteoarthritis who have been experiencing pain more than 8 weeks

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
DEVICE	CKD-981(1)	20 minutes per day, 5 days a week for 6 weeks.
DEVICE	CKD-981(2)	20 minutes per day, 5 days a week for 6 weeks.
DEVICE	Sham device	20 minutes per day, 5 days a week for 6 weeks.
DRUG	Reference Drug	QD for 6 weeks
DRUG	Placebo Drug	QD for 6 weeks

Timeline

• Start date: 2025-04-28
• Primary completion: 2025-10-28
• Completion: 2025-10-28
• First posted: 2025-05-02
• Last updated: 2026-04-13

Locations

1 site across 1 country: South Korea