NCT06954389

Hyperbaric Oxygen Therapy as a Neuroprotective Modality in Pediatric Acquired Brain Injury With Motor Disability

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Kafrelsheikh University · Academic / Other
• Sex: All
• Age: 4 Years – 12 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to assess the efficacy of hyperbaric oxygen therapy as a neuroprotective intervention in children with acquired brain injury.

Detailed description

Pediatric acquired brain injury (ABI) represents a significant challenge in modern medicine, necessitating innovative therapeutic approaches to enhance recovery and minimize long-term neurological deficits. Hyperbaric oxygen therapy (HBOT), which delivers oxygen at pressures exceeding atmospheric levels, has emerged as a promising neuroprotective intervention for various forms of pediatric brain injury, including traumatic brain injury (TBI), anoxic-ischaemic encephalopathy (AIE), and stroke.

Conditions

• Hyperbaric Oxygen Therapy
• Neuroprotective
• Pediatric
• Acquired Brain Injury
• Motor Disability

Interventions

Type	Name	Description
OTHER	Hyperbaric oxygen therapy	Patients received hyperbaric oxygen therapy using a monochamber hyperbaric chamber in addition to conventional rehabilitation.
OTHER	Conventional rehabilitation	Patients received conventional rehabilitation alone.

Timeline

• Start date: 2024-03-01
• Primary completion: 2024-10-01
• Completion: 2024-10-01
• First posted: 2025-05-01
• Last updated: 2025-05-01

Locations

1 site across 1 country: Egypt