NCT06953830

Optimal Measurement of Spleen Stiffness Among Veterans With Metabolic Dysfunction-Associated Steatotic Liver Disease

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: William Jennings Bryan Dorn VA Medical Center · Federal
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

A growing number of people are being diagnosed with fatty liver disease, also known as metabolic-dysfunction associated liver disease (MASLD). Fatty liver disease can unknowingly progress to serious liver disease and even permanent scarring (cirrhosis).The purpose of this research is to learn the best way to detect serious liver disease as early as possible in patients with fatty liver disease by measuring the stiffness of the spleen. Secondarily, the study hopes to understand how the stiffness of the spleen relates to the severity of liver disease.

Conditions

• Metabolic-dysfunction-associated Fatty Liver Disease (MAFLD)

Interventions

Type	Name	Description
DEVICE	Vibration-controlled transient elastography	Liver and spleen stiffness measurements using vibration-controlled transient elastography

Timeline

• Start date: 2025-04-08
• Primary completion: 2026-06-01
• Completion: 2026-07-01
• First posted: 2025-05-01
• Last updated: 2025-05-01

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study