NCT06950476

ART Cycle Outcomes When Only 1 to 3 Oocytes Are Retrieved

Assisted Reproductive Technology Cycle Outcomes When Only 1 to 3 Oocytes Are Retrieved: a Retrospective Analysis of 3,671 Cycles in Poor Responders From a Large Volume Single Center

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 3,761 (actual)
• Sponsor: Istituto Clinico Humanitas · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

This is a monocentric retrospective observational study. The study focuses on the women who underwent Assisted Reproductive Technology (ART) cycles with poor ovarian response (POR), defined as \<4 oocytes retrieved. The objectives of the study are as follows: * Evaluate clinical pregnancy rate (CPR) and cumulative live birth rate (CLBR) in women with poor ovarian response. * Evaluate abortion rate in women with poor ovarian response. * Evaluate the influence of patient characteristics (age, Anti-Müllerian hormone \[AMH\] levels, Antral Follicle Count \[AFC\], Follicle Stimulating Hormone \[FSH\], Body Mass Index \[BMI\]) on women with poor ovarian response. To address the study objectives, data will be collected using a specific internal web-based database. All oocyte retrieval procedures performed at the Humanitas Fertility Center from January 2010 to December 2023 will be included in the evaluation. Outcomes will be expressed in terms of CLBR, CPR and Abortion Rate.

Conditions

• Infertility Assisted Reproductive Technology
• Oocyte Retrieval

Interventions

Type	Name	Description
PROCEDURE	Oocyte Retrieval	Oocyte retrieval is performed at the end of ovarian stimulation (OS) to collect oocytes for use in IVF or ICSI cycles.

Timeline

• Start date: 2010-01-01
• Primary completion: 2023-12-31
• Completion: 2023-12-31
• First posted: 2025-04-30
• Last updated: 2025-05-07