NCT06949020

A Dose-finding Study of JMKX003142 in Treatment of Cardiac Edema

Efficacy and Safety of JMKX003142 Injection in Heart Failure Patients With Volume Overload：A Phase II, Randomized, Double-blind, Placebo-controlled Study

• Status: Not Yet Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 160 (estimated)
• Sponsor: Jemincare · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To Evaluate the Safety, Efficacy, and Pharmacokinetic/Pharmacodynamics Characteristics of JMKX003142 injection Administered Randomly,Double-blind, Placebo-controlled Study in Chinese Cardiacl Edema Patients.

Conditions

• Cardiac Edema

Interventions

Type	Name	Description
DRUG	JMKX003142 Injection	JMKX003142 injection for experimental groups once daily for five days.
DRUG	JMKX003142 Injection	JMKX003142 injection for experimental groups once daily for five days.
DRUG	JMKX003142 Injection	JMKX003142 injection for experimental groups once daily for five days.
DRUG	JMKX003142 placebo	JMKX003142 placebo for placebo groups once daily for five days.

Timeline

• Start date: 2025-06-01
• Primary completion: 2027-01-31
• Completion: 2027-05-31
• First posted: 2025-04-29
• Last updated: 2025-04-29