NCT06947616

Effect of Mild Therapeutic Hypothermia on the Doses of Vasopressors and Inotropes in Cardiogenic Shock Complicating Acute Myocardial Infarction

Effect of Mild Therapeutic Hypothermia on the Doses of Vasopressors and Inotropes in Cardiogenic Shock Complicating Acute Myocardial Infarction: A Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 50 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The study aimed to assess the effects of mild therapeutic hypothermia (MTH) on vasopressors and inotropes in patients with cardiogenic shock (CS) due to acute myocardial infarction (AMI).

Detailed description

Cardiogenic shock (CS) is a condition characterized by a severe lack of blood flow to vital organs caused by primary malfunction of the heart, as described by the European Society of Cardiology (ESC) and the American Heart Association (AHA). Acute myocardial infarction (AMI) is a prevalent etiology of CS, constituting a minimum of 30% of the instances. 50% of CS cases manifest upon hospital admission, whereas the remaining 50% occur after hospital admission.

Conditions

• Mild Therapeutic Hypothermia
• Cardiogenic Shock
• Acute Myocardial Infarction
• Vasopressors
• Inotropes

Interventions

Type	Name	Description
DRUG	Mild therapeutic hypothermia	Patients received mild therapeutic hypothermia (MTH) to 33°C for 24-36 h

Timeline

• Start date: 2020-10-01
• Primary completion: 2022-10-01
• Completion: 2022-10-01
• First posted: 2025-04-27
• Last updated: 2025-04-27

Locations

1 site across 1 country: Egypt