NCT06945393

ANTIPIGMENTING OR DEPIMENTING EFFICACY UNDER PART OF VISIBLE LIGHT

EVALUATION OF THE EFFICACY OF ANTIPIGMENTING OR DEPIMENTING AGENTS UNDER PART OF VISIBLE LIGHT [400-450NM] EXPOSURES

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 30 (actual)
• Sponsor: L'Oreal · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The study intends to validate a protocol and define a positive reference to evaluate the efficacy of anti-pigmenting and depigmenting agents under part of visible Light exposures, between 400nm to 450nm. It is carried out on cosmetic products for which the safety has been assured by a toxicologist, with the aim of confirming the efficacy of the products, which will be used by a large number of consumers under normal and reasonably foreseeable use conditions.

Detailed description

The main objective of this study is to assess the efficacy of antipigmenting or depigmenting agents under \[400-450nm\] exposure in healthy volunteers by skin colorimetry (Delta E). The secondary objectives are: * To assess the efficacy of antipigmenting or depigmenting agents under \[400-450nm\] exposure in healthy volunteers by clinical evaluation and additional colorimetry measurements (Delta L\*, a\*, b\* and ITA°) and clinical evaluation. * To assess the local tolerance and safety of the topical formulations under \[400-450nm\] exposure by recording adverse events and safety.

Conditions

• Visible Light Exposure on Healthy Back Skin

Interventions

Type	Name	Description
OTHER	Cosmetic topical products	Cosmetic topical products efficacy evaluation

Timeline

• Start date: 2021-10-21
• Primary completion: 2022-05-21
• Completion: 2022-05-21
• First posted: 2025-04-25
• Last updated: 2025-04-25

Locations

1 site across 1 country: Romania