NCT06945380

Evaluating a Mobile Health Application Intervention for Caregiver Instruction in Manual Therapy for Chemotherapy-Induced Peripheral Neuropathy

mHealth App for Caregiver Instruction in Manual Therapy for Chemotherapy-Induced Peripheral Neuropathy

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This clinical trial assesses the impact of a family caregiver-delivered massage technique for use in cancer survivors with chemotherapy-induced peripheral neuropathy (CIPN). CIPN is a common cancer treatment side effect that impairs quality of life and daily functioning. Aside from the relatively transient effects of chemotherapy treatment (e.g., nausea, diarrhea, vomiting, infections, fatigue, hair loss), chemotherapy can damage nervous system structures leading to long-term CIPN effects including numbness in hands or feet, "pins and needles" or sudden stabbing pains, difficulty buttoning clothing or picking up objects, loss of balance and risk of falling, difficulty driving (steering wheel, foot pedals), and increased sensitivity to heat or cold. Caregivers who lack effective strategies of supportive care are at risk of feeling helpless, overwhelmed or frustrated watching their loved one suffer. Oncology massage (OM) teaches oncology-informed modifications, adaptations and safety precautions for a cancer survivor's specific condition, treatment history and side effects. An mobile health application (app) for caregivers can teach care for CIPN using safe oncology-informed massage techniques at home. Using the Peripheral Neuropathy Relief (PNR) program in the form of relaxation may help for stress reduction, reduced CIPN symptoms, and/or an increased sense of connection with patients and their family caregiver.

Conditions

• Chemotherapy-Induced Peripheral Neuropathy
• Malignant Solid Neoplasm
• Hematopoietic and Lymphatic System Neoplasm

Interventions

Type	Name	Description
OTHER	Best Practice, Comparator Program	Receive access to a comparator program
OTHER	Best Practice, Usual Care	Receive usual care
OTHER	Internet-Based Intervention	Receive access to the PNR program
PROCEDURE	Massage Therapy	Perform the relaxation massage techniques
OTHER	Survey Administration	Complete surveys to assess CIPN symptoms, overall well-being and quality of life, and caregiver reaction and attitudes

Timeline

• Start date: 2025-05-27
• Primary completion: 2026-03-31
• Completion: 2026-03-31
• First posted: 2025-04-25
• Last updated: 2026-02-27

Locations

1 site across 1 country: United States