NCT06944418

The Study of Differences in Eosinophil Function and Subsets in Patients With Eosinophilic Pulmonary Diseases

The Study of Differences in Eosinophil Function and Subsets in Patients With Eosinophilic Pulmonary Diseases Based on Flow Cytometry Analysis

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: Peking Union Medical College Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Accepted

Summary

The study subjects of this research are patients with eosinophil-associated pulmonary diseases, including eosinophilic granulomatosis with polyangiitis, idiopathic hypereosinophilic syndrome, idiopathic acute eosinophilic pneumonia, idiopathic chronic eosinophilic pneumonia, and primary simple pulmonary eosinophilia. The aim is to detect eosinophil subtypes in peripheral blood based on surface protein expression, to understand the differences in eosinophil subtypes among patients with different diseases, to elucidate the significance of different eosinophil subtypes, and ultimately to provide a theoretical basis for the selection of treatment directions for patients.

Conditions

• Eosinophil Subtype
• Eosinophilic Pulmonary Diseases

Interventions

Type	Name	Description
OTHER	observation	observation

Timeline

• Start date: 2024-01-01
• Primary completion: 2026-01-01
• Completion: 2027-01-01
• First posted: 2025-04-25
• Last updated: 2025-04-25

Locations

1 site across 1 country: China