NCT06942702

Efficacy of Genicular Block on Total Knee Arthroplasty Surgery

Assesment of Postoperative Analgesic Efficacy of Preoperatively Applied Genicular Block on Total Knee Arthroplasty: A Randomized Controlled Study

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 44 (estimated)
• Sponsor: Mersin University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to investigate the postoperative pain relieving effect of preoperative genicular block in total knee arthroplasty surgery. The main questions it aims to answer are: 1. Do visual analog scale (VAS) scores decrease in patients who underwent geniculate block? 2. Does opioid consumption decrease in patients who underwent geniculate block? Researchers will compare postoperative pain in patients who received genicular block with those who did not.One group of patients will be administered 0.25% bupivacaine with the geniculate block method. The other group will not undergo any intervention. Both groups will be administered intravenous morphine for postoperative analgesia.

Detailed description

Patients scheduled for knee arthroplasty will be randomly assigned into two groups. One group will receive a genicular nerve block prior to surgery without the administration of general anesthesia, while the other group will not undergo any interventional procedure. The genicular nerve block will be administered in three quadrants around the knee, with each injection consisting of 5 mL of 0.25% Marcaine. All injections will be performed by investigator MA. Patient assessments will be conducted by investigator MO. Postoperative intravenous analgesia will be provided to both groups.

Conditions

• Total Knee Anthroplasty
• Genicular Nerves Block

Interventions

Type	Name	Description
DRUG	Genicular blocks (bupivakain)	Genicular block is a regional analgesic technique performed with USG
DRUG	Patient Control Analgesia (PCA) Morphine group	this group consists of the patients no any intervention preoperatively and they will be given morfin with PCA (Patient controlled analgesia) and paracetamol 3x1000 mg intravenous and diclofenac 75 mg intramuscular (if needed)
DRUG	Paracetamol (acetaminophen) + Diclofenac Sodium	All patients are given paracetamol (3x1000 mg) and diclofenac (if needed)

Timeline

• Start date: 2025-12-20
• Primary completion: 2026-10-20
• Completion: 2026-12-20
• First posted: 2025-04-24
• Last updated: 2025-12-23