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Trials / Recruiting

RecruitingNCT06941870

Efanesoctocog Alfa Prophylaxis in Patients With Hemophilia A With Synovial Hypertrophy

Prospective Interventional Study of Effectiveness of Efanesoctocog Alfa Prophylaxis on Synovial Hypertrophy in Patients With Hemophilia A

Status
Recruiting
Phase
Phase 4
Study type
Interventional
Enrollment
35 (estimated)
Sponsor
Sanofi · Industry
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

The objective of the study is to assess the improvement of synovial hypertrophy during the 12 months of efanesoctocog alfa prophylaxis once per week (QW) in joints with existing evidence of synovial hypertrophy in participants with hemophilia A. The study duration for each participant is approximately 12 months.

Conditions

Interventions

TypeNameDescription
DRUGEfanesoctocog alfaPharmaceutical form:Lyophilized powder in a sterile vial that requires reconstitution with sterile water for injection (diluent)-Route of administration:Intravenous

Timeline

Start date
2025-09-23
Primary completion
2027-10-25
Completion
2027-10-25
First posted
2025-04-24
Last updated
2025-11-18

Locations

13 sites across 4 countries: United States, Canada, Japan, Taiwan

Regulatory

Source: ClinicalTrials.gov record NCT06941870. Inclusion in this directory is not an endorsement.

Efanesoctocog Alfa Prophylaxis in Patients With Hemophilia A With Synovial Hypertrophy (NCT06941870) · Clinical Trials Directory