NCT06940479

Evaluating Changes in Synovial Fluid Before and After GAE for Knee Osteoarthritis

Genicular Artery Embolization for Knee Osteoarthritis: Evaluation of the Correlation Between Subjective Symptom Response and Objective Measures of Inflammation

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 46 (estimated)
• Sponsor: University of Colorado, Denver · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to learn if genicular artery embolization (GAE) can improve knee pain and decrease inflammation in adults with knee osteoarthritis. The main question it aims to answer is: \- Does the GAE procedure improve knee pain and decrease inflammation? Researchers will compare synovial fluid samples taken from the knee before and after the procedure. Participants will: * Have a contrast enhanced MRI before and after the procedure * Complete performance-based measures before and after the procedure * Complete questionnaires before and after the procedure

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
PROCEDURE	GAE procedure	Genicular artery embolization

Timeline

• Start date: 2025-07-16
• Primary completion: 2027-07-01
• Completion: 2028-07-01
• First posted: 2025-04-23
• Last updated: 2026-03-24

Locations

1 site across 1 country: United States