NCT06939023

Laparoscopic Versus Robot-assisted Left-sided Pancreatectomy for Benign and Pre-malignant Lesions (DIPLOMA-3)

Laparoscopic Versus Robot-assisted Left-sided Pancreatectomy for Benign and Pre-malignant Lesions (DIPLOMA-3): an International Multicenter Patient-blinded Randomized Controlled Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 256 (estimated)
• Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The DIPLOMA-3 trial is an international, multicenter, patient-blinded randomized controlled trial comparing laparoscopic and robot-assisted left-sided pancreatectomy. Patients with an indication for elective left-sided pancreatecomy for benign or premalignant lesions in the body or tail of the pancreas and considered eligible will be randomized between laparoscopic and robot-assisted resection.

Conditions

• Pancreatectomy
• Distal Pancreatectomy (DP)
• Pancreatic Neoplasms
• Pancreatic Adenoma
• Pancreatic Cyst
• Pancreatic Cystadenoma
• Surgery
• Minimally Invasive Surgical Technique
• Minimally Invasive Distal Pancreatectomy
• Minimally Invasive Surgery

Interventions

Type	Name	Description
PROCEDURE	Laparoscopic minimally invasive left-sided pancreatecomy	Laparoscopic minimally invasive left-sided pancreatecomy
PROCEDURE	Robot-assisted minimally invasive left-sided pancreatecomy	Robot-assisted minimally invasive left-sided pancreatecomy

Timeline

• Start date: 2025-06-01
• Primary completion: 2027-06-01
• Completion: 2028-06-01
• First posted: 2025-04-22
• Last updated: 2025-09-04

Locations

1 site across 1 country: Netherlands