Trials / Recruiting
RecruitingNCT06937528
Use of Extracellular Vesicles (EV) for Knee Osteoarthrosis
Knee Osteoarthrosis (KOA) in Jordanian Patients: a Phase I Dose-finding Study Using Extracellular Vesicles (EV) for Advanced Stage III and IV KOA
- Status
- Recruiting
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- Sponsor
- University of Jordan · Academic / Other
- Sex
- All
- Age
- 42 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
Extracellular vesicles (EV) will be injected in patients diagnosed with Knee osteoarthrosis
Detailed description
50 patients from both genders diagnosed with Knee osteoarthrosis, will be enrolled according to strict inclusion and exclusion criteria. These patients will be injected with Extracellular vesicles (EV). Then, they are followed by clinical assessment, laboratory investigations as well as magnetic resonance imaging (MRI) of the injected knee.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Extracellular vesicles | Intra-articular extravascular vesicles injection. |
Timeline
- Start date
- 2024-01-01
- Primary completion
- 2026-01-30
- Completion
- 2027-01-30
- First posted
- 2025-04-22
- Last updated
- 2025-04-22
Locations
1 site across 1 country: Jordan
Source: ClinicalTrials.gov record NCT06937528. Inclusion in this directory is not an endorsement.