NCT06937515

MELASYL EFFICACY UNDER PART OF VISIBLE LIGHT

EVALUATION OF THE EFFICACY OF AN ANTIMELANOGENESIS AGENT (MELASYL) IN DIFFERENT CONCENTRATIONS UNDER PART OF VISIBLE LIGHT [400-450NM] EXPOSURES AND UNDER FULL VISIBLE LIGHT [400-700NM] EXPOSURES

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 31 (actual)
• Sponsor: L'Oreal · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The study intends to evaluate the efficacy of an anti-melanogenesis active in different concentrations under part of visible Light \[400-450nm\] exposures and under full visible light \[400-700nm\] exposures. It is carried out on cosmetic products for which the safety has been assured by a toxicologist, with the aim of confirming the efficacy of the products, which will be used by a large number of consumers under normal and reasonably foreseeable use conditions.

Detailed description

The main objective of this study is to assess the efficacy of an anti-melanogenesis active in different concentrations under \[400-450nm\] exposures and under \[400-700nm\] in healthy volunteers by skin colorimetry (Delta E). The secondary objectives are: * To assess the efficacy of anti-melanogenesis active in different concentrations under \[400-450nm\] exposures and under \[400-700nm\] exposures in healthy volunteers by clinical evaluation and additional colorimetry measurements (Delta L\*, a\*, b\* and ITA°). * To assess the local tolerance and safety of the topical formulations under \[400-450nm\] exposure and under \[400-700nm\] by recording adverse events and safety.

Conditions

• Visible Light Exposure on Healthy Back Skin

Interventions

Type	Name	Description
OTHER	Cosmetic topical products	Cosmetic topical products efficacy evaluation

Timeline

• Start date: 2023-03-27
• Primary completion: 2023-09-01
• Completion: 2023-09-01
• First posted: 2025-04-22
• Last updated: 2025-04-22

Locations

1 site across 1 country: Romania