NCT06937190

Pre-Sleep Creatine Enhances Anaerobic Power in Recreationally Active Females

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: Ankara Yildirim Beyazıt University · Academic / Other
• Sex: Female
• Age: 18 Years – 25 Years
• Healthy volunteers: Accepted

Summary

This study is a randomized, double-blind, placebo-controlled trial designed to examine the effects of pre-sleep creatine monohydrate supplementation on anaerobic performance and muscle damage markers in recreationally active females. Participants will be randomly assigned to receive either 5 grams of creatine monohydrate or a placebo 30 minutes before sleep for seven consecutive days. Anaerobic performance will be assessed using the Wingate Anaerobic Test, evaluating peak and average power output and fatigue index. Blood samples will be collected before and after the supplementation period to analyze markers of muscle damage, including creatine kinase and lactate dehydrogenase. This study aims to provide insight into the efficacy of short-term, time-specific creatine supplementation for enhancing performance and recovery.

Conditions

• Anaerobic Performance
• Sports Nutrition
• Exercise Recovery
• Muscle Fatigue
• Creatine Supplementation
• Recreational Physical Activity
• Female Athletes

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Creatine Monohydrate	Participants will receive 5 grams of creatine monohydrate powder dissolved in water, flavored with a sugar-free agent, 30 minutes before sleep each night for 7 days.
DIETARY_SUPPLEMENT	Placebo (Maltodextrin)	Visually identical placebo (maltodextrin powder, 5 g/day), flavored with a sugar-free agent, dissolved in water and consumed 30 minutes before sleep for 7 consecutive days.

Timeline

• Start date: 2025-04-01
• Primary completion: 2025-05-10
• Completion: 2025-07-10
• First posted: 2025-04-22
• Last updated: 2025-04-22

Locations

1 site across 1 country: Iran