NCT06937047

Efficacy and Safety of Cold Versus Hot Snare Polypectomy for Removal of 4-10 mm Pedunculated Colorectal Polyps

Efficacy and Safety of Cold Versus Hot Snare Polypectomy for Removal of 4-10 mm Pedunculated Colorectal Polyps: a Randomized Controlled Trial

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 196 (estimated)
• Sponsor: Shandong University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This was a non-inferiority randomized controlled trial designed to compare the efficacy and safety of cold versus hot snare polypectomy for the removal of 4-10 mm pedunculated colorectal polyps. The primary outcome was delayed postpolypectomy bleeding. The secondary outcomes included immediate postpolypectomy bleeding, procedure time, en bloc resection, complete histologic resection, use of haemostatic clips and perforation rate.

Conditions

• Colorectal Polyps

Interventions

Type	Name	Description
PROCEDURE	cold snare polypectomy	Cold snare polypectomy was conducted for the removal of 4-10 mm pedunculated colorectal polyps.
PROCEDURE	hot snare polypectomy	Hot snare polypectomy was conducted for the removal of 4-10 mm pedunculated colorectal polyps.

Timeline

• Start date: 2025-05-06
• Primary completion: 2027-01-01
• Completion: 2027-02-28
• First posted: 2025-04-20
• Last updated: 2025-04-29

Locations

1 site across 1 country: China