NCT06935448

Effect of an Enhanced Recovery After Surgery Program on Outcomes After Pancreatoduodenectomy

Effect of an Enhanced Recovery After Surgery Program on Outcomes After Pancreatoduodenectomy; Experience From Two Referral Centers in Central Greece.

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 170 (estimated)
• Sponsor: University of Thessaly · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study assesses whether patients with pancreatic cancer who undergo surgery experience improved outcomes following the implementation of a multidisciplinary care pathway, specifically an enhanced recovery after surgery (ERAS) program. This pathway includes various interventions in the preoperative, intraoperative, and postoperative care of these patients, all aimed at enhancing their health status and postoperative results.

Detailed description

This prospective observational study is conducted by the same surgical team at two high-volume pancreatic cancer referral centers in Greece. Patients undergoing elective pancreatic surgery are prospectively enrolled and managed according to a standardized ERAS protocol (ERAS group). A control group, which received standard perioperative care before the implementation of ERAS, was retrospectively selected and matched based on demographic and clinical parameters. The primary study endpoint is the length of hospital stay (LOS), while secondary endpoints include 30-day mortality and morbidity.

Conditions

• Pancreatectomy
• Enhanced Recovery After Surgery
• Pancreatic Cancer Resectable

Interventions

Type	Name	Description
OTHER	enhanced recovery after surgery	ERAS group follows the enhanced recovery after surgery program which involves 20 elements

Timeline

• Start date: 2019-07-01
• Primary completion: 2025-04-30
• Completion: 2025-05-30
• First posted: 2025-04-20
• Last updated: 2025-04-20

Locations

1 site across 1 country: Greece