NCT06935110

Feasibility of Tracheobronchial Defect Reconstruction Using Allogenic Aortic Patch

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The investigators investigate the feasibility and safety of using cryopreserved aortic patches for tracheal or bronchial defect repair.

Conditions

• Trachea Diseases
• Airway Remodeling
• Reconstruction Surgery

Interventions

Type	Name	Description
PROCEDURE	Cryopreserved aortic patch	After identifying the tracheal or bronchial defect with standard surgical techniques, the airway gap is reconstructed with a patch of human cryopreserved (-80 celsius degree) aortic allograft, which was not matched by the ABO and leukocyte antigen systems. The anastomosis is performed with standard technique for airway anastomosis. An silicon stent is inserted to prevent collapse for the aortic graft.

Timeline

• Start date: 2025-09-15
• Primary completion: 2029-07-31
• Completion: 2029-10-01
• First posted: 2025-04-20
• Last updated: 2025-12-03

Locations

2 sites across 1 country: Taiwan