NCT06933290

Effect of Flavored, Carbonated Drinks on Salivary Flow, Salivary Composition, and Taste Perceptions

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 13 (estimated)
• Sponsor: PepsiCo Global R&D · Industry
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

To determine the effect of flavored, carbonated drinks on salivary flow rate, saliva composition, and taste perceptions compared with control drinks (water, carbonated water, non-carbonated)

Detailed description

Previous studies have shown that drinking a beverage can stimulate the production of saliva and alter its composition. These effects could impact oral processing and taste perceptions. Various ingredients in beverages such as carbonation may affect saliva and oral processing. The objective of this study is to determine the effect of flavored carbonated beverages on salivary flow rate, saliva composition (pH, mucins, carbonic anhydrase, and total protein), and taste perceptions compared with unflavored and non-carbonated control drinks.

Conditions

• Taste Perception
• Saliva Production

Interventions

Type	Name	Description
OTHER	Beverage	15 milliliter aliquot interspersed with tastants with a 3 minute break between tastants

Timeline

• Start date: 2025-03-24
• Primary completion: 2025-06-13
• Completion: 2025-06-29
• First posted: 2025-04-18
• Last updated: 2025-04-18

Locations

1 site across 1 country: United States