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Active Not RecruitingNCT06926842

Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes (ZUPREME 2)

A Randomized, Double-Blind, Phase 2 Trial of Once-Weekly Petrelintide Compared With Placebo in Participants With Overweight or Obesity and Type 2 Diabetes

Status
Active Not Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
221 (actual)
Sponsor
Zealand Pharma · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The main purpose of this study is to investigate efficacy and safety of three doses of petrelintide versus placebo in participants with overweight or obesity and type 2 diabetes.

Conditions

Interventions

TypeNameDescription
DRUGPetrelintidePetrelintide will be taken by participants once weekly subcutaneously.
OTHERPlaceboMatching placebo to petrelintide will be taken by participants once weekly subcutaneously.

Timeline

Start date
2025-04-22
Primary completion
2026-08-13
Completion
2026-08-13
First posted
2025-04-15
Last updated
2026-01-15

Locations

48 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT06926842. Inclusion in this directory is not an endorsement.

Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes (ZUPREME 2) (NCT06926842) · Clinical Trials Directory