NCT06921642

Simplified Inferior Vena Cava Collapsiblity

"Performance of a Simplified Inferior Vena Cava Collapsibility Methodology to Predict Preload Responsiveness (PR) in Spontaneously Breathing and Critically Ill Patients"

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 74 (actual)
• Sponsor: University Hospital, Lille · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Fluid administration is a cornerstone therapy in critically ill patient. Fluid restriction or overload can therefore change patient's outcome and mortality. Close monitoring of PR (capacity of increase the cardiac output after fluid therapy) is recommended by experts' guidelines. Few bedside simple tests are available to predict PR in spontaneously breathing patients. A team of investigators from Lille (Roger Salengro hospital) have already showed that inferior vena cava collapsibility (cVCI) accuracy of prediction of PR is excellent in standardized sponteanous breathing patient. However, the standardized inspiration maneuver remains challenging because requiring specific and non-widely available equipment.

Detailed description

The primary objective of this study is to confirmed the excellent accuracy of cVCI to predict PR when standardized inspiratory maneuver is simplified. The secondary objective is to test cVCIs in different period of cardiac cycle guided by electrocardiogram. After receiving a loyal information patients will give their non-objection. During systematic echocardiography, patients will have to breathe in different conditions in order to homogenize their inspiratory effort. This maneuver will be repeated three times.

Conditions

• Circulatory Failure

Interventions

Type	Name	Description
DEVICE	Echocardiography images	Addition of a recording loop during routine ultrasound, during which the patient is in simplified standardized ventilation

Timeline

• Start date: 2023-06-06
• Primary completion: 2024-06-07
• Completion: 2024-06-07
• First posted: 2025-04-10
• Last updated: 2025-04-10

Locations

1 site across 1 country: France