NCT06921187

Study of Auditory Perception After Progressive Exposure to Aversive Sounds in People With Misophonia

Etude de la Perception Auditive après Exposition PROgressive Aux Sons Aversifs Chez Des Personnes MISophonEs

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 110 (estimated)
• Sponsor: Institut Pasteur · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The primary objective of the project is to characterise and measure the auditory perception of subjects with misophonia compared with the auditory perception of control subjects.

Conditions

• Misophonia

Interventions

Type	Name	Description
BEHAVIORAL	Psychoacoustic test	Natural sounds will be presented at different decibels (dB), and the subject will be asked to rate the pleasantness/unpleasantness of the sound heard on a visual analogue scale, as well as the loudness (subjective intensity) of the sound heard.
OTHER	semi-structured interviews	interview, designed under the supervision of a psychologist and using the methodology of micro-phenomenological interviews the aim of these interviews is to gain access to the participants' experiences, as they describe them in the first person, during misophonic episodes
OTHER	Exposure to unpleasant sounds	Home exposure is a practice whereby participants voluntarily subject themselves to SMs in a controlled environment. Participants will be asked to complete two tasks: firstly, they will have to expose themselves to all 10 sounds at least twice a week; secondly, they will have to record the annoyance felt for each sound and the subjective loudness (loudness) of each SM using VAS.

Timeline

• Start date: 2025-06-01
• Primary completion: 2026-03-01
• Completion: 2026-03-01
• First posted: 2025-04-10
• Last updated: 2025-04-10

Locations

2 sites across 1 country: France