NCT06919328

Absorption and Tolerability of Injectable Administration of Niagen®+, as Compared to NAD+

Absorption and Tolerability of Injectable Administration of Niagen®+, Nicotinamide Riboside Chloride, a Specialized Form of Vitamin B3, as Compared to NAD+: a Double Blinded, Randomized, Controlled Clinical Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Nutraceuticals Research Institute · Academic / Other
• Sex: All
• Age: 40 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This study evaluates the subjective effects of injection administration of NR on healthy adult populations.

Detailed description

The purpose of this work is to explore the tolerability of Niagen®, nicotinamide riboside chloride, a specialized form of vitamin B3, via intramuscular (IM), subcutaneous (SQ), and intravenous-push (IVP) administration, in comparison to NAD+, an active comparator, administered through the same routes.

Conditions

• Healthy Aging

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Niagen®	nicotinamide riboside
OTHER	NAD+	Nicotinamide adenine dinucleotide
OTHER	Placebo	bacteriostatic water

Timeline

• Start date: 2024-10-31
• Primary completion: 2025-04-30
• Completion: 2025-06-30
• First posted: 2025-04-09
• Last updated: 2025-04-09

Locations

1 site across 1 country: United States