NCT06918327

Effect of CGF on Postoperative Pain After Third Molar Surgery

The Power of Concentrated Growth Factor: A New Era in Pain Management in Third Molar Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 49 (actual)
• Sponsor: Ege University · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the effects of concentrated growth factor (CGF) on pain after bilateral impacted third molar surgery and to determine its contribution to the healing process. The main question it aims to answer is: Is CGF effective on reducing the pain in impacted third molar surgery? Researchers compare the pain on the CGF-applied and CGF free sides after impacted third molar surgery. Postoperative pain is assessed using the Visual Analogue Scale. TThe postoperative outcomes including pain are clinically assessed at different-time intervals (1-7 days).

Conditions

• Oral Complication

Interventions

Type	Name	Description
OTHER	Concentrated Growth Factor	Bilaterally impacted third molar of the patients are removed surgically and concentrated growth factor is placed in one of the extraction sockets.
OTHER	non-CGF	The other extraction socket is left empty for control purposes.

Timeline

• Start date: 2017-05-01
• Primary completion: 2018-01-01
• Completion: 2018-06-05
• First posted: 2025-04-09
• Last updated: 2025-04-20

Locations

1 site across 1 country: Turkey (Türkiye)