Trials / Recruiting
RecruitingNCT06917053
Renal Perfusion and the Development of AKI Following Traumatic Injury
Renal Perfusion and the Development of AKI Following Traumatic Injury - A Longitudinal Observational Cohort Study
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 20 (estimated)
- Sponsor
- King's College Hospital NHS Trust · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Acute kidney injury (AKI) is a complication of traumatic haemorrhagic shock (THS) and together these conditions increase mortality risk. Although septic shock patients who develop severe AKI are known to develop hypoperfusion of the renal cortex, little is known regarding intra-renal perfusion changes in THS. The aim of the current study is to investigate the effects of THS on renal microcirculatory perfusion.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Ultrasound (including contrast enhanced ultrasound) | Ultrasound measures: contrast enhanced ultrasound (CEUS) of the kidney, venous excess ultrasound (VExUS), echocardiography |
| DEVICE | Sublingual incident dark field videomicroscopy | Sublingual incident dark field (IDF) videomicroscopy |
| DEVICE | Urinary oxygen tension. | Continuous urinary oxygen tension |
Timeline
- Start date
- 2024-04-13
- Primary completion
- 2026-01-01
- Completion
- 2026-07-01
- First posted
- 2025-04-08
- Last updated
- 2025-04-08
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT06917053. Inclusion in this directory is not an endorsement.