NCT06915831

Type 1 Diabetes and Obstructive Sleep Apnea

Obstructive Sleep Apnea and Glycemic Dysregulation in Adults With Type 1 Diabetes

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: University of Chicago · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to investigate the role of sleep apnea in glycemic dysregulation in adults with Type 1 diabetes.

Detailed description

Obstructive sleep apnea (OSA) is a common sleep disorder characterized by recurrent collapse of upper airway during sleep, resulting in intermittent hypoxia, sleep fragmentation by transient arousals, and poor sleep quality. Continuous positive airway pressure (CPAP), applied at night, is considered the treatment of choice for persons who are diagnosed with OSA. Current evidence suggests that OSA is highly prevalent in adults with T1D and particularly those with moderate-to-severe OSA have poorer glycemic control. Our overall goal is to investigate the role OSA in glycemic dysregulation in adults with T1D.

Conditions

• Sleep Apnea, Obstructive
• Type 1 Diabetes (T1D)

Interventions

Type	Name	Description
DEVICE	Continuous positive airway pressure (CPAP)	All-night CPAP will be applied with bedtimes 23:00h to 7:00h.

Timeline

• Start date: 2025-11-10
• Primary completion: 2029-08-31
• Completion: 2029-08-31
• First posted: 2025-04-08
• Last updated: 2026-01-20

Locations

1 site across 1 country: United States