Trials / Recruiting
RecruitingNCT06911229
Neurophysiology of Locomotor Adaptation and Freezing of Gait in Parkinson's Disease
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- Sponsor
- University of Florida · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Locomotor adaptation will be studied using an established split-belt treadmill paradigm, consisting of baseline (1:1 speed ratio), split-belt adaptation (2:1) and post-adaptation (1:1) walking. Split-belt walking will be performed under DBS ON and DBS OFF conditions, while off-medication.
Detailed description
We will test the hypotheses that DBS can facilitate split-belt walking adaptation with DBS ON compared with DBS OFF.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Deep Brain Stimulation (DBS) | Patients will receive DBS in the clinically-optimized setting. |
Timeline
- Start date
- 2025-08-01
- Primary completion
- 2028-12-31
- Completion
- 2028-12-31
- First posted
- 2025-04-04
- Last updated
- 2025-08-27
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT06911229. Inclusion in this directory is not an endorsement.