NCT06908863

Correlations Between Fine Manual Motor Skills and Speech Articulation

Cortical Correlations Between Fine Manual Motor Skills and Speech Articulation : Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Centre Hospitalier Universitaire de Nice · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to examine the relationship between cerebral motor control during a manual task and during an articulary task, using functional MRI in a cohort or young adults aged between 18 and 35. The literature reveals a well-established relationship between manual motor skills and speech from an anatomical and functional point of view. Some studies indicate a proximity between the motor cortical regions corresponding to the hand and the mouth, with a mutual interaction of the two functions from the earliest stages of life (for example, the Babkin reflex). Experimental data shows that hand movements can be influenced by mouth movements. Neurophysiological studies have demonstrated the existence of a link between these two systems in humans and monkeys. To date, no study has identified the common cortical networks that are active during these two limb movements in a given sample of subjects. The aim of this study is to determine whether such networks exist. The results could be therapeutically relevant, particularly for stroke patients, by enabling more effective restoration of articulatory abilities through complementary limb movements.

Conditions

• Correlations Between Cerebral Motor Control During a Manual Task and During an Articulatory Task

Interventions

Type	Name	Description
OTHER	Tasks learning and MRI scan	\- 2-week learning and training phase of motor tasks and oral and facial language (OLF) tasks. Manual fine motor tasks will correspond to activities requiring increasing precision and different types of grip (crushing a ball, modelling clay with the palm of the hand, sorting round coins with thumb/index pliers). The OLF praxis tasks will correspond to coordinated movements of different parts of the face (cheeks, lips and tongue). \- MRI (magnetic resonance imaging) exam, During this exam, the investigator will give to the subject instructions for a task to be carried out. These tasks will correspond to the motor tasks previously trained.

Timeline

• Start date: 2025-10-13
• Primary completion: 2026-01-01
• Completion: 2026-02-04
• First posted: 2025-04-03
• Last updated: 2026-03-19

Locations

1 site across 1 country: France