NCT06907758

Impact of Perioperative Organ Resuscitation of Brain-dead Deceased Organ Donor on Kidney Graft Function in the Recipient

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: University Hospital, Strasbourg, France · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

Brain-dead patients are the primary source of grafts for those awaiting organ transplantation. Recommendations exist for the management of these potential donors, based on the concept of organ resuscitation, according to which targeted resuscitation would improve graft quality and quantity. Graft performance thus depends on fixed factors (donor/recipient age, medical history, etc.) but also potentially modifiable factors. Through this study, the investigators aim to identify potentially modifiable factors in our donor care (in intensive care and the operating room) that may influence graft function in the recipient. For simplicity, the investigators will focus on kidney grafts. The aim is to improve the effectiveness of the transplant and reduce waiting times.

Conditions

• Kidney Graft

Timeline

• Start date: 2024-04-10
• Primary completion: 2025-12-10
• Completion: 2025-12-10
• First posted: 2025-04-02
• Last updated: 2025-04-02

Locations

1 site across 1 country: France