NCT06907368

Analysis of the Functional Impact of Total Knee Arthroplasty Using Quantified Gait Analysis and Proprioceptive Evaluation

Analysis of the Functional Impact of Total Knee Arthroplasty Using Quantified Gait Analysis and Proprioceptive Evaluation. Prospective, Single-center, Open-label Study, Cohort Follow-up.

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 15 (estimated)
• Sponsor: University Hospital, Grenoble · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Total knee arthroplasty remains the gold standard in the management of disabling gonarthrosis. Improved functional results, increased availability of care and an ageing population have all contributed to the rise in total knee replacement surgery in Western countries. Surgical techniques have been steadily improving for several decades in terms of implant positioning and joint alignment. However, 10% of patients are dissatisfied with the clinical and functional results. The challenge is to understand why these patients remain dissatisfied despite these surgical advances. Our aim is to understand the functional impact of knee prosthesis through a quantified analysis of gait, the performance of certain tasks of daily living, and pre- and post-operative proprioceptive assessments. We will link these results with patient feedback to identify factors potentially responsible for poor postoperative outcomes.

Conditions

• Total Knee Arthroplasty for Gonarthrosis

Interventions

Type	Name	Description
OTHER	Quantitative Gait Analysis	The following explorations will be carried out pre-operatively (pre-OP), then post-operatively at 3 months (post-OP3) and 12 months (post-OP12) : * Quantified gait analysis (QGA) * Functional tests (mechanical analysis of everyday tasks): * SIT-TO-STAND test (test consisting of standing up and sitting down on a chair) * STEP INITIATION test (test consisting of walking up a step and then down) * Proprioceptive tests : * Joint Position Sense (JPS) (angle memorization and reproduction test at the knee joint) * OBSTACLE CLEARANCE test (test consisting in simulating the clearance of an obstacle) * Questionnaires : * Functional questionnaires : * KSS (Knee Society Score) * SKV (Simple knee value) * KOOS (Knee Injury and Osteoarthritis Outcome Score) * Quality of life (EQ5D-5L) The total duration of each exploration session is estimated at 1 hour .

Timeline

• Start date: 2025-04-01
• Primary completion: 2027-10-01
• Completion: 2027-10-01
• First posted: 2025-04-02
• Last updated: 2025-04-02

Locations

1 site across 1 country: France