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Trials / Not Yet Recruiting

Not Yet RecruitingNCT06906978

Single Cell Acute Leukemia Analysis

Status
Not Yet Recruiting
Phase
N/A
Study type
Interventional
Enrollment
40 (estimated)
Sponsor
Assistance Publique Hopitaux De Marseille · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Numerous chemotherapy and immunotherapy resistance genes have been identified in cancers in general and acute myeloid leukemia in particular. As a preliminary to this study, the investigators hypothesized the co-expression of these genes in the same cell as a major factor in relapse. This hypothesis was supported in vitro by the study of the evolution of these co-expressions after incubation with chemotherapy drugs. The current study aims to verify this hypothesis by studying the expression of these genes in single-cell samples from relapsed acute myeloid leukemia patients.

Conditions

Interventions

TypeNameDescription
PROCEDUREblood samplingPatients will be seen in hospital as part of their routine care, during which a blood test will be prescribed. On this occasion, an additional 20 mlof blood will be collected for research purposes.

Timeline

Start date
2025-07-31
Primary completion
2028-07-31
Completion
2029-07-31
First posted
2025-04-02
Last updated
2025-04-10

Source: ClinicalTrials.gov record NCT06906978. Inclusion in this directory is not an endorsement.

Single Cell Acute Leukemia Analysis (NCT06906978) · Clinical Trials Directory