NCT06902285

Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty

Use of Magnesium-L-Threonate to Improve Subjective Sleep Quality After Total Joint Arthroplasties: Randomized Controlled Clinical Trial

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 64 (estimated)
• Sponsor: University of Miami · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The study team is conducting a study to see if Magnesium-L-Threonate (MgT) can help improve how well participants sleep and reduce pain after total joint replacement surgery

Conditions

• Sleep
• Knee Osteoarthritis

Interventions

Type	Name	Description
DRUG	Magnesium Threonate	Participants will receive a daily 145 mg pill by mouth 30 minutes before going to sleep
OTHER	Control	Participants will receive two sugar pills daily by mouth 30 minutes before going to sleep

Timeline

• Start date: 2025-04-21
• Primary completion: 2026-05-01
• Completion: 2026-05-01
• First posted: 2025-03-30
• Last updated: 2025-04-24

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study