NCT06901791

Efficacy of Lactobacillus Rhamnosus LRa05 in Gestational Diabetes

Assessing the Efficacy of Lactobacillus Rhamnosus LRa05 in Improving Blood Glucose and Gut Microbiota in Patients With Gestational Diabetes

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Wecare Probiotics Co., Ltd. · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

This study aims to comprehensively evaluate the multifaceted impacts of Lactobacillus rhamnosus LRa05 on patients with gestational diabetes. Initially, the study will investigate the effects of LRa05 on improving patients' blood glucose levels and gut microbiota. Additionally, the study will assess the impact of this strain on patients' blood lipid levels, inflammatory markers, and body mass index (BMI). Furthermore, the study will also focus on its effects on thyroid function, vaginal microbiota, and bile acid metabolism in patients with gestational diabetes.

Conditions

• GDM

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Conventional treatment and Probiotic	Participants will continuously take Lactobacillus rhamnosus LRa05 from the time of enrollment until delivery.

Timeline

• Start date: 2025-04-10
• Primary completion: 2025-07-31
• Completion: 2026-03-10
• First posted: 2025-03-30
• Last updated: 2025-03-30

Locations

1 site across 1 country: China