NCT06900569

Ashwagandha Supplementation for Prevention of Muscle Damage

Ashwagandha Supplementation for Recovery From Muscle-damaging Exercise and Sleep Quality

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 19 (actual)
• Sponsor: University of Saskatchewan · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

Ashwagandha is an herbal supplement that has a wide range of benefits related to exercise when supplemented for about 8-12 weeks. This study aims to investigate whether short-term Ashwagandha supplementation can enhance muscle recovery following exercise by measuring muscle strength recovery, swelling, and soreness in the biceps.

Detailed description

The purpose of the study is to determine the effects of Ashwagandha supplementation on recovery from muscle-damaging exercise. Ten to twenty participants will be randomized to receive Ashwagandha supplementation (600 mg/d) or placebo for 10 days. On day 7, participants will perform a muscle damaging exercise session (six sets of concentric and emphasized eccentric repetitions with the biceps). Before and after exercise and at 24, 48, and 72 hours after exercise, isometric muscle strength, muscle swelling (ultrasound), and muscle soreness will be assessed. The investigators hypothesize the Ashwagandha will alleviate symptoms of muscle damage (swelling and soreness) and enhance strength recovery after a bout of muscle-damaging exercise.

Conditions

• Muscle Damage

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Ashwagandha	600 mg/d Ashwagandha
DIETARY_SUPPLEMENT	Placebo	600 mg/d placebo

Timeline

• Start date: 2025-03-22
• Primary completion: 2025-04-30
• Completion: 2025-05-15
• First posted: 2025-03-28
• Last updated: 2026-02-23

Locations

1 site across 1 country: Canada