Trials / Enrolling By Invitation
Enrolling By InvitationNCT06900244
Metabolic Imaging of Neurological Disease
Probing Metabolic Dysregulation and Altered Substrate Metabolism in the Healthy and Disrupted Brain Using Hyperpolarised 13C Labelled Substrates.
- Status
- Enrolling By Invitation
- Phase
- —
- Study type
- Observational
- Enrollment
- 250 (estimated)
- Sponsor
- University of Oxford · Academic / Other
- Sex
- All
- Age
- 99 Years
- Healthy volunteers
- Accepted
Summary
Multiple Sclerosis is a chronic condition that shows changes in the way that the brain consumes sugar. It is also known that there are a number of metabolic and inflammatory sequelae following a transient ischemic attack/stroke (hereby referred to collectively as 'stroke'). This study will use a powerful new technology ('hyperpolarised magnetic resonance imaging') to detect these changes in the brains of people with multiple sclerosis and Clinically Isolated Syndrome (CIS) or following a stroke when compared to a group of healthy volunteers. It will be undertaken at the University of Oxford, and each participant will undergo up to 4 scans over the course of three years.
Conditions
Timeline
- Start date
- 2021-07-01
- Primary completion
- 2027-06-01
- Completion
- 2027-06-01
- First posted
- 2025-03-28
- Last updated
- 2025-03-28
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT06900244. Inclusion in this directory is not an endorsement.