NCT06899347

The Role of Prophylactic Central Compartment Neck Dissection in the Management of 2 to 4 Cm Papillary Thyroid Carcinoma

Impact of PROphylactic Central COMpArtment Neck Dissection for 2-4 Cm Papillary Thyroid Carcinoma

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 196 (estimated)
• Sponsor: Leonardo Rossi · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This randomized prospective study aims to evaluate the advantages and disadvantages (both oncologic and surgical) of prophylactic central compartment neck dissection for clinically node-negative 2-4 cm papillary thyroid carcinoma patients who have been treated either with total thyroidectomy alone or with total thyroidectomy + prophylactic central compartment neck dissection .

Conditions

• Papillary Thyroid Carcinoma
• Central Compartment Neck Dissction
• Thyroidectomy

Interventions

Type	Name	Description
PROCEDURE	Total Thyroidectomy + Central Compartment Neck Dissection	Thyroidectomy will be performed with the patient in the supine position with the neck hyperextended. A 3 to 6 cm transverse cervicotomy, two fingers above the sternal notch, will be performed, and the midline will be opened. After the inferior laryngeal nerve and parathyroids are visualized, the thyroidectomy will be achieved. When performed, pCCND will aim at removing the nodes of Level VI, which has been reported to contain the thyroid gland and the adjacent nodes bordered superiorly by the hyoid bone, inferiorly by the brachiocephalic artery, and laterally on each side by the carotid sheaths

Timeline

• Start date: 2025-04-01
• Primary completion: 2026-04-01
• Completion: 2035-04-01
• First posted: 2025-03-27
• Last updated: 2025-03-27