NCT06898476

Silkworm Pupa Powder Improves Dementia.

A Prospective, Double-Blind, Randomized Controlled Trial Evaluating Silkworm Pupa Powder Versus Placebo in Improving Alzheimer's Disease Among Patients

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Zhejiang Provincial Tongde Hospital · Academic / Other
• Sex: All
• Age: 50 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this clinical trial is to determine whether silkworm pupa powder is effective in treating Alzheimer's disease. It will also investigate whether silkworm pupa powder can improve the nutritional and frailty status of patients with Dementia. The main questions it aims to answer are: * Will silkworm pupa powder improve the daily living conditions of patients with Alzheimer's disease? * Will silkworm pupa powder improve the nutritional status and frailty of Alzheimer's disease patients? Researchers will compare silkworm pupa powder with a placebo (a similar substance containing 0.5% silkworm pupa powder) to see if silkworm pupa powder can treat Alzheimer's disease. Participants will: * Take silkworm pupa powder or placebo daily for four months; * Visit the clinic for check-ups and tests every four weeks; * Record their symptoms and various physiological indicators.

Conditions

• Alzheimer Disease(AD)
• Sarcopenia
• Asthenia

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Silkworm pupa powder	Silkworm pupa powder, 2 times a day, two packets (12\*2 g) each time, take with warm water, before meals, for three months
DIETARY_SUPPLEMENT	Placebo	Placebo, 2 sachets (12\*2 g) twice a day, with warm water, before meals, for three months

Timeline

• Start date: 2025-04-10
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2025-03-27
• Last updated: 2025-05-04

Locations

1 site across 1 country: China