NCT06896994

Esketamine Combined Pregabalin and Duloxetine for Postherpetic Neuralgia

Intravenous Infusion of Esketamine in Combination With Pregabalin and Duloxetine for Postherpetic Neuralgia

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: Beijing Tiantan Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To assess the 1-week effects and safety of esketamine in combination with pregabalin and duloxetine to relieve pain in patients with postherpetic Neuralgia(PHN).

Detailed description

The investigators aim to investigate whether or not esketamine combined with pregabalin and duloxetine to relieve pain in patients with PHN, and seek a rapid, effective and safe treatment for refractory patients with PHN

Conditions

• Postherpetic Neuralgia

Interventions

Type	Name	Description
DRUG	esketamine group	In the esketamine group, in addition to receiving the combination of pregabalin and duloxetine, patients will also undergo a single intravenous infusion of esketamine.
DRUG	control group	receiving the combination of pregabalin and duloxetine

Timeline

• Start date: 2025-04-01
• Primary completion: 2026-04-01
• Completion: 2026-05-01
• First posted: 2025-03-26
• Last updated: 2025-04-27

Locations

1 site across 1 country: China