Trials / Recruiting
RecruitingNCT06892197
Comparing Hydrocortisone and Prednisolone for Community Acquired Pneumonia (CAP)
- Status
- Recruiting
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 1,600 (estimated)
- Sponsor
- Copenhagen Respiratory Research · Network
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The goal of this cluster randomized controlled trial is to determine the optimal treatment for community aquired pneumonia (CAP). The study compares the effects and side effects of hydrocortisone and prednisolone in patients above 18 years old diagnosed with severe CAP. The main question is whether there is a difference in all cause mortality within thirty days. Participants will be randomized to receive treatment with either hydrocortisone or prednisolone.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Methylprednisolone (drug) | ATC code: H02AB06. Can be changed to Prednisolone 50 mg orally. |
| DRUG | hydrocortisone | ATC-code: H02AB09. Can be changed to 50 mg x 4 daily orally if appropriate. |
Timeline
- Start date
- 2026-03-10
- Primary completion
- 2030-08-01
- Completion
- 2030-11-01
- First posted
- 2025-03-24
- Last updated
- 2026-03-18
Locations
14 sites across 1 country: Denmark
Source: ClinicalTrials.gov record NCT06892197. Inclusion in this directory is not an endorsement.