Trials / Recruiting
RecruitingNCT06890897
Esketamine Combined Pulsed Radiofrequency for Acute/Subacute Zoster-associated Trigeminal Neuralgia
Effect of Intravenous Infusion of Esketamine Combined Pulsed Radiofrequency on Acute/Subacute Zoster-associated Trigeminal Neuralgia
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 174 (estimated)
- Sponsor
- Beijing Tiantan Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
To assess the 1-month effects and safety of esketamine combined PRF and standardized treatment to relieve pain in patients with acute/subacute zoster-related trigeminal neuralgia(ZRTN).
Detailed description
The investigators aim to investigate whether or not esketamine combined PRF and standardized treatment to relieve pain in patients with acute/subacute ZRTN , and seek a safe, and effective treatment for refractory patients with ZRTN
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Esketamine group | Patients in the esketamine group will receive intravenous infusion of esketamine besides PRF+standardized treatment.The formula will be intravenous infusion of 0.5mg/kg of esketamine diluted in 50 mL normal saline, starting with intravenous injection of 10 mg of esketamine for 1 minute, and maintaining a dose 8 mg/h.The infusion rate will be adjusted the parameter according to the tolerance of the patients |
| DRUG | PRF group | Patients in the control group will receive PRF+standardized treatment |
Timeline
- Start date
- 2025-04-01
- Primary completion
- 2026-06-30
- Completion
- 2026-09-30
- First posted
- 2025-03-24
- Last updated
- 2025-04-27
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06890897. Inclusion in this directory is not an endorsement.