NCT06890234

Tissue Microdialysis Monitoring of Liver Grafts

Clinical Applicability of Tissue Microdialysis for Early Assessment of Liver Graft Metabolism in Patients After Orthotopic Liver Transplantation

• Status: Enrolling By Invitation
• Phase: —
• Study type: Observational
• Enrollment: 25 (estimated)
• Sponsor: University Medical Centre Ljubljana · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study will investigate the dynamics of metabolic molecules sampled from human liver grafts during the early postoperative period using tissue microdialysis. The obtained tissue samples will be compared with standard liver function tests and dynamic functional liver assessment tests. The primary objective is to evaluate the clinical feasibility, utility, and non-inferiority of tissue microdialysis in comparison to current standard methods for monitoring liver grafts.

Conditions

• Liver Transplantation
• Liver Graft Dysfunction
• Tissue Metabolism

Timeline

• Start date: 2022-05-11
• Primary completion: 2025-08-01
• Completion: 2025-12-31
• First posted: 2025-03-21
• Last updated: 2025-03-21

Locations

1 site across 1 country: Slovenia