Trials / Recruiting
RecruitingNCT06889987
Bilateral Ultrasound Guided Intramuscular Quadratus Lumborum Plane Block Versus Bilateral Lateral Quadratus Lumborum Plane Block in Controlling Postoperative Pain in Cancer Patients Undergoing Open Nephrectomy
Efficacy of Bilateral Ultrasound Guided Intramuscular Quadratus Lumborum Plane Block (Ql4) Versus Bilateral Lateral Quadratus Lumborum Plane Block (Ql1) in Controlling Post-Operative Pain in Cancer Patient Undergoing Open Nephrectomy: A Randomized Control Study
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 90 (estimated)
- Sponsor
- National Cancer Institute, Egypt · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
This study aims to evaluate the efficacy of bilateral ultrasound-guided intramuscular quadratus lumborum plane block (QL4) versus bilateral lateral quadratus lumborum plane block (QL1) in controlling postoperative pain in cancer patients undergoing open nephrectomy.
Detailed description
Post-surgical somatic pain is very distressing to patients, which may lead to significant complications. Practitioners initially used these as ilioinguinal, iliohypogastric, rectus sheath blocks, and in the early 21st century, transversus abdominis plane (TAP) blocks. A recent variation of the TAP block is known as the quadratus lumborum block (QLB). The QL block effectiveness is believed to result from the spread of Local Anesthetic cranially from the lumbar deposition into the thoracic paravertebral space (TPVS). So, the QLB seems to relieve somatic and visceral pains.
Conditions
- Bilateral
- Ultrasound
- Intramuscular Quadratus Lumborum Plane Block
- Lateral Quadratus Lumborum Plane Block
- Postoperative Pain
- Cancer Patients
- Open Nephrectomy
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Intramuscular quadratus lumborum block | Patients will receive bilateral ultrasound-guided intramuscular quadratus lumborum block with an injection of 0.4 ml/kg bupivacaine 0.25% after induction of general anesthesia |
| DRUG | Lateral quadratus lumborum block | Patients will receive bilateral ultrasound-guided lateral quadratus lumborum with an injection of 0.4 ml/kg of bupivacaine 0.25 after induction of general anesthesia. |
| DRUG | General anesthesia | Patients will receive only general anesthesia without any block. |
Timeline
- Start date
- 2024-12-10
- Primary completion
- 2025-12-06
- Completion
- 2025-12-06
- First posted
- 2025-03-21
- Last updated
- 2025-03-21
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT06889987. Inclusion in this directory is not an endorsement.