NCT06889753

A Clinical Trial to Investigate the Effect of Pollen Extracts on Menopausal Symptoms in Healthy Women.

A Randomized, Triple-blind, Placebo Controlled, Parallel Clinical Trial to Investigate the Effect of Pollen Extracts on Menopausal Symptoms in Healthy Women.

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Graminex LLC · Academic / Other
• Sex: Female
• Age: 45 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The goal of this study is to investigate the effect of pollen extracts on menopausal symptoms in healthy women The main question it aims to answer is: What is the difference in change in severity of menopausal symptoms as assessed by the total Menopause Rating Scale (MRS) score from baseline at Week 36 between Graminex Water Soluble Pollen Extract (WSPE), Lipid Soluble Pollen Extract (LSPE), and Placebo? Participants will be asked to complete the MRS assessment tool to rate their menopausal symptoms while receiving either WSPE, LSPE, or Placebo.

Conditions

• Menopausal Women

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Graminex WSPE	Graminex Water Soluble Pollen Extract is standardized to 6% amino acids.
DIETARY_SUPPLEMENT	Graminex LSPE	Graminex Lipid Soluble Pollen Extract is standardized to 7% phytosterols.
DIETARY_SUPPLEMENT	Placebo	Placebo

Timeline

• Start date: 2025-10-29
• Primary completion: 2026-08-01
• Completion: 2026-08-01
• First posted: 2025-03-21
• Last updated: 2025-11-19

Locations

1 site across 1 country: Canada