NCT06887452

Pharmacist-Led Treat-to-Target Urate Lowering Therapy in Patients With Gout

Pharmacist-Led Treat-to-Target Urate Lowering Therapy in Patients in Gout (Pharm-UP) Study

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 310 (estimated)
• Sponsor: VA Office of Research and Development · Federal
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study will compare two different approaches to manage medications that lower uric acid levels. This study will be conducted at five VA medical centers across the United States and will take 4-5 years to complete. Individual participation will last up to two years.

Detailed description

This project will quantify and compare the effects of a pharmacist-led telehealth-delivered intervention versus usual care on arthritis flare burden and serum urate goal achievement in 310 U.S. Veterans with gout enrolled from five VA medical centers. The project will quantify the effects of the intervention on patient-reported outcomes (improvements in health-related quality of life, pain interference, and participant global assessment).

Conditions

• Gout
• Gouty Arthritis

Interventions

Type	Name	Description
OTHER	Pharmacist-Led	Pharmacist will conduct regular telehealth visits with Veterans during dose escalation phase of gout treatment

Timeline

• Start date: 2026-10-01
• Primary completion: 2029-10-01
• Completion: 2031-03-30
• First posted: 2025-03-20
• Last updated: 2026-02-19

Locations

5 sites across 1 country: United States