NCT06884189

Application of Plant Protection Products (PPP) in Apple Orchards

Pilot Study on the Exposure of Operators, Residents and Workers to Plant Protection Products Used in Apple Orchards and Possible Health Effects

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 16 (estimated)
• Sponsor: German Federal Institute for Risk Assessment · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aim of the aPPPle pilot study is to test feasibility and generate first results in preparation for a main study. The aPPPle study will investigate the exposure of operators, workers and residents to plant protection products (PPP) and potential physiological effects on blood biomarkers. The target plants are apple crops, as application occurs at higher altitudes and therefore higher drift/exposure is expected compared to ground-level application. The substances to be investigated are acetamiprid (an insecticide) and dithianon and dodine (two fungicides).

Conditions

• Dermal Exposure
• Inhalative Exposure
• Metabolites in Urine
• Effekt Biomarker in Blood

Timeline

• Start date: 2025-03-11
• Primary completion: 2025-12-20
• Completion: 2025-12-20
• First posted: 2025-03-19
• Last updated: 2025-03-19

Locations

1 site across 1 country: Germany